I quit using Quicksave the first time that happened to me (which was NOT in Skyrim, think it might have been Daggerfall). And I never bother loading autosaves as they're all too likely to be corrupted anyway.
I always have ZILLIONS of hard saves - I usually save at least every 5 minutes. Yup, I'm totally anal about that.
Loving fantasy since 1960 or so, FRPGs since 1975 (appx), and CRPGs since 1985....
When the Dark comes rising, six shall turn it back,
Three from the Circle, three from the track;
Wood, bronze, iron; water, fire, stone:
Five will return, and one go on alone.